Human NPAS4 activation kit by CRISPRa

SKU GA116949

NPAS4 CRISPRa kit - CRISPR gene activation of human neuronal PAS domain protein 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NPAS4
• Locus ID: 266743
• Components:

  GA116949G1, NPAS4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116949G2, NPAS4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116949G3, NPAS4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001318804, NM_178864
• UniProt ID: Q8IUM7
• Synonyms: bHLHe79; Le-PAS; NXF; PASD10
• Summary: NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008]