Human ASC2 (PYDC1) activation kit by CRISPRa

SKU
GA116933
PYDC1 CRISPRa kit - CRISPR gene activation of human pyrin domain containing 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PYDC1
Locus ID 260434
Components

GA116933G1, ASC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116933G2, ASC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116933G3, ASC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_152901
UniProt ID Q8WXC3
Synonyms ASC2; cPOP1; POP1; PYC1
Summary Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN411240 PYDC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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