Human ETFBKMT activation kit by CRISPRa

SKU GA116765

ETFBKMT CRISPRa kit - CRISPR gene activation of human electron transfer flavoprotein subunit beta lysine methyltransferase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ETFBKMT
• Locus ID: 254013
• Components:

  GA116765G1, ETFBKMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116765G2, ETFBKMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116765G3, ETFBKMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001135863, NM_001135864, NM_173802
• UniProt ID: Q8IXQ9
• Synonyms: C12orf72; ETFB-KMT; METTL20
• Summary: Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria (PubMed:25023281, PubMed:25416781). Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain (PubMed:25416781).[UniProtKB/Swiss-Prot Function]