Human MSRB3 activation kit by CRISPRa

SKU GA116758

MSRB3 CRISPRa kit - CRISPR gene activation of human methionine sulfoxide reductase B3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MSRB3
• Locus ID: 253827
• Components:

  GA116758G1, MSRB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116758G2, MSRB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116758G3, MSRB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001031679, NM_001193460, NM_001193461, NM_198080
• UniProt ID: Q8IXL7
• Synonyms: DFNB74
• Summary: The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]