Human Syntaxin binding protein 4 (STXBP4) activation kit by CRISPRa

SKU
GA116734
STXBP4 CRISPRa kit - CRISPR gene activation of human syntaxin binding protein 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STXBP4
Locus ID 252983
Components

GA116734G1, Syntaxin binding protein 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116734G2, Syntaxin binding protein 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116734G3, Syntaxin binding protein 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_178509
UniProt ID Q6ZWJ1
Synonyms Synip
Summary Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN415386 STXBP4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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