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Human NEIL2 activation kit by CRISPRa

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SKU
GA116733
NEIL2 CRISPRa kit - CRISPR gene activation of human nei like DNA glycosylase 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC200913 NEIL2 (Myc-DDK-tagged)-Human nei endonuclease VIII-like 2 (E. coli) (NEIL2), transcript variant 1
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Other products for "NEIL2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NEIL2
Locus ID 252969
Components

GA116733G1, NEIL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116733G2, NEIL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116733G3, NEIL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001135746, NM_001135747, NM_001135748, NM_145043, NM_001349439, NM_001349440, NM_001349441, NM_001349442, NR_146180, NR_146181, NR_146182
UniProt ID Q969S2
Synonyms NEH2; NEI2
Summary This gene encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN400913 NEIL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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