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Human AKR7L activation kit by CRISPRa

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SKU
GA116720
AKR7L CRISPRa kit - CRISPR gene activation of human aldo-keto reductase family 7 like (gene/pseudogene)
  $1,657.00
4 Weeks*

Other products for "AKR7L"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol AKR7L
Locus ID 246181
Components

GA116720G1, AKR7L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116720G2, AKR7L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116720G3, AKR7L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001145289, NM_201252, NR_040288, NR_040289
UniProt ID Q8NHP1
Synonyms AFAR3; AKR7A4
Summary This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. provided by RefSeq, Feb 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN406787 AKR7L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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