Human PRPS1L1 activation kit by CRISPRa

SKU GA116641

PRPS1L1 CRISPRa kit - CRISPR gene activation of human phosphoribosyl pyrophosphate synthetase 1 like 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRPS1L1
• Locus ID: 221823
• Components:

  GA116641G1, PRPS1L1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116641G2, PRPS1L1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116641G3, PRPS1L1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_175886
• UniProt ID: P21108
• Synonyms: PRPS1; PRPS3; PRPSL; PRS-III
• Summary: This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008]