Human MATH5 (ATOH7) activation kit by CRISPRa

SKU GA116567

ATOH7 CRISPRa kit - CRISPR gene activation of human atonal bHLH transcription factor 7

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ATOH7
• Locus ID: 220202
• Components:

  GA116567G1, MATH5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116567G2, MATH5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116567G3, MATH5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_145178
• UniProt ID: Q8N100
• Synonyms: bHLHa13; Math5; NCRNA; PHPVAR; RNANC
• Summary: This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011]