Human USP12 activation kit by CRISPRa

SKU
GA116474
USP12 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 12
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol USP12
Locus ID 219333
Components

GA116474G1, USP12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116474G2, USP12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116474G3, USP12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_182488
UniProt ID O75317
Synonyms UBH1; USP12L1
Summary Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN405355 USP12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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