Human PTCRA activation kit by CRISPRa

SKU GA116247

PTCRA CRISPRa kit - CRISPR gene activation of human pre T cell antigen receptor alpha

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PTCRA
• Locus ID: 171558
• Components:

  GA116247G1, PTCRA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116247G2, PTCRA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116247G3, PTCRA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001243168, NM_001243169, NM_001243170, NM_138296
• UniProt ID: Q6ISU1
• Synonyms: PT-ALPHA; PTA
• Summary: The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]