Human DCP2 activation kit by CRISPRa

SKU GA116155

DCP2 CRISPRa kit - CRISPR gene activation of human decapping mRNA 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DCP2
• Locus ID: 167227
• Components:

  GA116155G1, DCP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116155G2, DCP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116155G3, DCP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001242377, NM_152624, NR_038352
• UniProt ID: Q8IU60
• Synonyms: NUDT20
• Summary: The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]