Human EXDL1 (EXD1) activation kit by CRISPRa

SKU
GA116035
EXD1 CRISPRa kit - CRISPR gene activation of human exonuclease 3'-5' domain containing 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol EXD1
Locus ID 161829
Components

GA116035G1, EXDL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116035G2, EXDL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116035G3, EXDL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001286441, NM_152596
UniProt ID Q8NHP7
Synonyms EXDL1
Summary RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN406223 EXD1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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