Human TMTC2 activation kit by CRISPRa

SKU GA115998

TMTC2 CRISPRa kit - CRISPR gene activation of human transmembrane O-mannosyltransferase targeting cadherins 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TMTC2
• Locus ID: 160335
• Components:

  GA115998G1, TMTC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115998G2, TMTC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115998G3, TMTC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001320321, NM_001320322, NM_152588
• UniProt ID: Q8N394
• Synonyms: IBDBP1
• Summary: The protein encoded by this gene is an integral membrane protein localized to the endoplasmic reticulum (ER). The encoded protein contains many tetratricopeptide repeats, sequences known for being involved in protein-protein interactions. This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin, and it appears to play a role in calcium homeostasis in the ER. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]