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Human USP51 activation kit by CRISPRa

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SKU
GA115980
USP51 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 51
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA325185 USP51 Antibody (Center)
400 ul
$645.00
RC214303 USP51 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 51 (USP51)
10 ug
$651.00

Other products for "USP51"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol USP51
Locus ID 158880
Components

GA115980G1, USP51 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115980G2, USP51 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115980G3, USP51 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_201286
UniProt ID Q70EK9
Synonyms deubiquitinating enzyme 51; ubiquitin-specific processing protease 51; ubiquitin carboxyl-terminal hydrolase 51; ubiquitin specific peptidase 51; ubiquitin specific protease 51; ubiquitin thiolesterase 51
Summary Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN414303 USP51 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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