Human ABCA13 activation kit by CRISPRa

SKU GA115894

ABCA13 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily A member 13

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ABCA13
• Locus ID: 154664
• Components:

  GA115894G1, ABCA13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115894G2, ABCA13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115894G3, ABCA13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_152555, NM_152701
• UniProt ID: Q86UQ4
• Synonyms: DKFZp313D2411; FLJ16398; FLJ33876; FLJ33951
• Summary: In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]