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Human PPM1L activation kit by CRISPRa

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SKU
GA115805
PPM1L CRISPRa kit - CRISPR gene activation of human protein phosphatase, Mg2+/Mn2+ dependent 1L
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA316170 Rabbit polyclonal anti-PPM1L antibody
100 ul
$380.00
RC218909 PPM1L (Myc-DDK-tagged)-Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L)
10 ug
$457.00

Other products for "PPM1L"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PPM1L
Locus ID 151742
Components

GA115805G1, PPM1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115805G2, PPM1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115805G3, PPM1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001317911, NM_001317912, NM_139245, NR_134243
UniProt ID Q5SGD2
Synonyms PP2C-epsilon; PP2CE; PPM1-LIKE
Summary The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN418909 PPM1L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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