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Human HSCB activation kit by CRISPRa

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SKU
GA115740
HSCB CRISPRa kit - CRISPR gene activation of human HscB mitochondrial iron-sulfur cluster cochaperone
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA507274 HSCB mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) 100 ul
$447.00
RC200843 HSCB (Myc-DDK-tagged)-Human HscB iron-sulfur cluster co-chaperone homolog (E. coli) (HSCB)
10 ug
$300.00

Other products for "HSCB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HSCB
Locus ID 150274
Components

GA115740G1, HSCB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115740G2, HSCB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115740G3, HSCB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001318314, NM_001318315, NM_001318316, NM_172002, NR_134560, NM_001363856
UniProt ID Q8IWL3
Synonyms DNAJC20; HSC20; JAC1
Summary This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants. provided by RefSeq, Dec 2015
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Other Versions
SKU Description Size Price
KN400843 HSCB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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