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Human RTN4RL1 activation kit by CRISPRa

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SKU
GA115577
RTN4RL1 CRISPRa kit - CRISPR gene activation of human reticulon 4 receptor like 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA331557 Rabbit Polyclonal Anti-RTN4RL1 Antibody
100 ul
$585.00
RC216415 RTN4RL1 (Myc-DDK-tagged)-Human reticulon 4 receptor-like 1 (RTN4RL1)
10 ug
$457.00

Other products for "RTN4RL1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RTN4RL1
Locus ID 146760
Components

GA115577G1, RTN4RL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115577G2, RTN4RL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115577G3, RTN4RL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_178568
UniProt ID Q86UN2
Synonyms NgR3; NGRH2
Summary Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis; protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity). Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development (PubMed:22325200). Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton (PubMed:22325200).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN416415 RTN4RL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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