Human POGLUT3 activation kit by CRISPRa

SKU
GA115474
POGLUT3 CRISPRa kit - CRISPR gene activation of human protein O-glucosyltransferase 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol POGLUT3
Locus ID 143888
Components

GA115474G1, POGLUT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115474G2, POGLUT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115474G3, POGLUT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_153705, NM_001363503, NM_001363502
UniProt ID Q7Z4H8
Synonyms MGC33424
Summary Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 (PubMed:30127001). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN406171 KDELC2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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