Human PABPC5 activation kit by CRISPRa

SKU GA115429

PABPC5 CRISPRa kit - CRISPR gene activation of human poly(A) binding protein cytoplasmic 5

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PABPC5
• Locus ID: 140886
• Components:

  GA115429G1, PABPC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115429G2, PABPC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115429G3, PABPC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_080832
• UniProt ID: Q96DU9
• Synonyms: PABP5
• Summary: This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]