Human GAB3 activation kit by CRISPRa

SKU
GA115348
GAB3 CRISPRa kit - CRISPR gene activation of human GRB2 associated binding protein 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GAB3
Locus ID 139716
Components

GA115348G1, GAB3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115348G2, GAB3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115348G3, GAB3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001081573, NM_001282283, NM_080612, NR_104114
UniProt ID Q8WWW8
Synonyms DOS/Gab family member 3; Gab3 protein; Gab3 scaffolding protein; GRB2-associated binding protein 3; OTTHUMP00000026055
Summary This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013
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Other Versions
SKU Description Size Price
KN417585 GAB3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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