Human SGCZ activation kit by CRISPRa

SKU GA115289

SGCZ CRISPRa kit - CRISPR gene activation of human sarcoglycan zeta

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SGCZ
• Locus ID: 137868
• Components:

  GA115289G1, SGCZ gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115289G2, SGCZ gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115289G3, SGCZ gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001322879, NM_001322880, NM_001322881, NM_139167
• UniProt ID: Q96LD1
• Synonyms: ZSG1
• Summary: The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix. [provided by RefSeq, Jul 2008]