Human SPATA18 activation kit by CRISPRa

SKU
GA115180
SPATA18 CRISPRa kit - CRISPR gene activation of human spermatogenesis associated 18
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPATA18
Locus ID 132671
Components

GA115180G1, SPATA18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115180G2, SPATA18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115180G3, SPATA18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001297608, NM_001346102, NM_001346103, NM_145263, NR_123728, NR_144359
UniProt ID Q8TC71
Synonyms Mieap; SPETEX1
Summary This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN405544 SPATA18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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