Human ZDHHC19 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ZDHHC19 |
| Locus ID | 131540 |
| Components |
GA115147G1, ZDHHC19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115147G2, ZDHHC19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115147G3, ZDHHC19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001039617, NM_144637, NR_135617, NR_135618 |
| UniProt ID | Q8WVZ1 |
| Synonyms | DHHC19 |
| Summary | Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS (PubMed:31462771, PubMed:20074548). Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer (PubMed:31462771). Palmitoylation of RRAS is linked to cell viability (PubMed:20074548). May be involved in S-stearoylation of STAT3 (Probable).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN421741 | ZDHHC19 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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