Human KCNH8 activation kit by CRISPRa

SKU GA115136

KCNH8 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily H member 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: KCNH8
• Locus ID: 131096
• Components:

  GA115136G1, KCNH8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115136G2, KCNH8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115136G3, KCNH8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_144633
• UniProt ID: Q96L42
• Synonyms: ELK; ELK1; elk3; Kv12.1
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. [provided by RefSeq, Jul 2008]