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Human CHMP4B activation kit by CRISPRa

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SKU
GA115067
CHMP4B CRISPRa kit - CRISPR gene activation of human charged multivesicular body protein 4B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA349803 Rabbit Polyclonal Anti-CHMP4B Antibody
100 ul
$205.00
RC207637 CHMP4B (Myc-DDK-tagged)-Human chromatin modifying protein 4B (CHMP4B)
10 ug
$300.00

Other products for "CHMP4B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CHMP4B
Locus ID 128866
Components

GA115067G1, CHMP4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115067G2, CHMP4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115067G3, CHMP4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_176812
UniProt ID Q9H444
Synonyms C20orf178; CHMP4A; CTPP3; CTRCT31; dJ553F4.4; Shax1; SNF7; SNF7-2; Vps32-2; VPS32B
Summary This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN407637 CHMP4B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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