Human PLD4 activation kit by CRISPRa

SKU GA114776

PLD4 CRISPRa kit - CRISPR gene activation of human phospholipase D family member 4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PLD4
• Locus ID: 122618
• Components:

  GA114776G1, PLD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114776G2, PLD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114776G3, PLD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001308174, NM_138790
• UniProt ID: Q96BZ4
• Synonyms: C14orf175
• Summary: 5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.[UniProtKB/Swiss-Prot Function]