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Human FCHO2 activation kit by CRISPRa

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SKU
GA114530
FCHO2 CRISPRa kit - CRISPR gene activation of human FCH domain only 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA326623 Rabbit Polyclonal FCHO2 Antibody
100 ug
$640.00
RC218124 FCHO2 (Myc-DDK-tagged)-Human FCH domain only 2 (FCHO2), transcript variant 1
10 ug
$589.00 $742.00

Other products for "FCHO2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol FCHO2
Locus ID 115548
Components

GA114530G1, FCHO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114530G2, FCHO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114530G3, FCHO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001146032, NM_138782
UniProt ID Q0JRZ9
Synonyms FCH domain only 2
Summary Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN418124 FCHO2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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