Human GNG8 activation kit by CRISPRa

SKU GA114340

GNG8 CRISPRa kit - CRISPR gene activation of human G protein subunit gamma 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: GNG8
• Locus ID: 94235
• Components:

  GA114340G1, GNG8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114340G2, GNG8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114340G3, GNG8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_033258
• UniProt ID: Q9UK08
• Synonyms: guanine nucleotide binding protein (G protein), gamma 8
• Summary: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.[UniProtKB/Swiss-Prot Function]