Human MARCHF9 activation kit by CRISPRa

SKU
GA114254
MARCH9 CRISPRa kit - CRISPR gene activation of human membrane associated ring-CH-type finger 9
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MARCHF9
Locus ID 92979
Components

GA114254G1, MARCHF9 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114254G2, MARCHF9 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114254G3, MARCHF9 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_138396
UniProt ID Q86YJ5
Synonyms MARCH-IX; RNF179
Summary MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 PubMed 14722266; Hoer et al., 2007 PubMed 17174307).supplied by OMIM, Apr 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN406159 MARCH9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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