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Human ARRDC1 activation kit by CRISPRa

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SKU
GA114234
ARRDC1 CRISPRa kit - CRISPR gene activation of human arrestin domain containing 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC207160 ARRDC1 (Myc-DDK-tagged)-Human arrestin domain containing 1 (ARRDC1)
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Other products for "ARRDC1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ARRDC1
Locus ID 92714
Components

GA114234G1, ARRDC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114234G2, ARRDC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114234G3, ARRDC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001317968, NM_152285
UniProt ID Q8N5I2
Summary Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN407160 ARRDC1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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