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Human LYK5 (STRADA) activation kit by CRISPRa

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SKU
GA114205
STRADA CRISPRa kit - CRISPR gene activation of human STE20 related adaptor alpha
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC221676 STRADA (Myc-DDK-tagged)-Human STE20-related kinase adaptor alpha (STRADA), transcript variant 1
10 ug
$457.00

Other products for "STRADA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STRADA
Locus ID 92335
Components

GA114205G1, LYK5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114205G2, LYK5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114205G3, LYK5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001003786, NM_001003787, NM_001003788, NM_001165969, NM_001165970, NM_153335, NM_001363786, NM_001363787, NM_001363789, NM_001363790, NM_001363791, NM_001363788, NR_156741
UniProt ID Q7RTN6
Synonyms LYK5; NY-BR-96; PMSE; Stlk; STRAD
Summary The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known. provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN414029 STRADA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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