Human CABLES1 activation kit by CRISPRa

SKU
GA114153
CABLES1 CRISPRa kit - CRISPR gene activation of human Cdk5 and Abl enzyme substrate 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CABLES1
Locus ID 91768
Components

GA114153G1, CABLES1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114153G2, CABLES1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114153G3, CABLES1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001100619, NM_001256438, NM_138375, NR_023359
UniProt ID Q8TDN4
Synonyms CABL1; CABLES; HsT2563; IK3-1
Summary This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jan 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN406794 CABLES1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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