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Human RNF185 activation kit by CRISPRa

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SKU
GA114116
RNF185 CRISPRa kit - CRISPR gene activation of human ring finger protein 185
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350363 Rabbit Polyclonal Anti-RNF185 Antibody
100 ul
$205.00
RC226760 RNF185 (Myc-DDK-tagged)-Human ring finger protein 185 (RNF185), transcript variant 3
10 ug
$150.00

Other products for "RNF185"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RNF185
Locus ID 91445
Components

GA114116G1, RNF185 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114116G2, RNF185 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114116G3, RNF185 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001135824, NM_001135825, NM_152267, NR_024209, NR_024210, NR_024211, NR_024212
UniProt ID Q96GF1
Synonyms BSK65-MONO1; BSK65-MONO2; BSK65-PANC1; BSK65-PANC2; BSK65-TEST1; BSK65-TEST2; BSK65-TEST3; FLJ38628; ring finger protein 185
Summary E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1 (PubMed:21931693). Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation (PubMed:27485036). Protects cells from ER stress-induced apoptosis (PubMed:27485036). Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway (PubMed:24019521). Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (PubMed:24019521).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN407827 RNF185 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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