Human SCARF2 activation kit by CRISPRa

SKU GA114093

SCARF2 CRISPRa kit - CRISPR gene activation of human scavenger receptor class F member 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SCARF2
• Locus ID: 91179
• Components:

  GA114093G1, SCARF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114093G2, SCARF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114093G3, SCARF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_153334, NM_182895
• UniProt ID: Q96GP6
• Synonyms: NSR1; SREC-II; SREC2; SRECRP-1; VDEGS
• Summary: The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]