Human STARD13 activation kit by CRISPRa

SKU GA114043

STARD13 CRISPRa kit - CRISPR gene activation of human StAR related lipid transfer domain containing 13

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: STARD13
• Locus ID: 90627
• Components:

  GA114043G1, STARD13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114043G2, STARD13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114043G3, STARD13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001243466, NM_001243474, NM_001243476, NM_052851, NM_178006, NM_178007, NM_178008
• UniProt ID: Q9Y3M8
• Synonyms: ARHGAP37; DLC2; GT650; LINC00464
• Summary: This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]