Human MLIP activation kit by CRISPRa

SKU GA114030

MLIP CRISPRa kit - CRISPR gene activation of human muscular LMNA interacting protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MLIP
• Locus ID: 90523
• Components:

  GA114030G1, MLIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114030G2, MLIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114030G3, MLIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001281746, NM_001281747, NM_138569
• UniProt ID: Q5VWP3
• Synonyms: C6orf142; CIP
• Summary: Required for precocious cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays an important role in protection against cardiac hypertrophy. Acts as a transcriptional cofactor, represses transactivator activity of ISL1 and MYOCD.[UniProtKB/Swiss-Prot Function]