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Human HEXO (ERI1) activation kit by CRISPRa

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SKU
GA114023
ERI1 CRISPRa kit - CRISPR gene activation of human exoribonuclease 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA504134 ERI1 mouse monoclonal antibody, clone OTI1B3 (formerly 1B3) 100 ul
$447.00
RC206777 ERI1 (Myc-DDK-tagged)-Human exoribonuclease 1 (ERI1)
10 ug
$686.00

Other products for "ERI1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ERI1
Locus ID 90459
Components

GA114023G1, HEXO gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114023G2, HEXO gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114023G3, HEXO gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_153332, NM_001354635, NM_001354636, NM_001354638
UniProt ID Q8IV48
Synonyms 3 HEXO; 3'HEXO; HEXO; THEX1
Summary RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN406777 ERI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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