Human LRRCC1 activation kit by CRISPRa

SKU GA113886

LRRCC1 CRISPRa kit - CRISPR gene activation of human leucine rich repeat and coiled-coil centrosomal protein 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LRRCC1
• Locus ID: 85444
• Components:

  GA113886G1, LRRCC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113886G2, LRRCC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113886G3, LRRCC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001077501, NM_033402, NM_001349636, NM_001349637, NM_001349638, NM_001349639
• UniProt ID: Q9C099
• Synonyms: Clerc; KIAA1764; leucine rich repeat and coiled-coil domain containing 1; SAP2; sodium channel associated protein 2
• Summary: This gene encodes a centrosomal protein that maintains the structural integrity of the centrosome and plays a key role in mitotic spindle formation. The encoded protein contains an N-terminal leucine-rich repeat domain and a C-terminal coiled-coil domain. It associates with the centrosome throughout the cell cycle and accumulates on the mitotic centrosome. [provided by RefSeq, Mar 2017]