OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human SHANK3 activation kit by CRISPRa

Be the first to review this product
SKU
GA113856
SHANK3 CRISPRa kit - CRISPR gene activation of human SH3 and multiple ankyrin repeat domains 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA320063 Rabbit Polyclonal SHANK3 Antibody
100 ug
$640.00
RC235332 SHANK3 (Myc-DDK tagged) - Homo sapiens SH3 and multiple ankyrin repeat domains 3 (SHANK3)
10 ug
$2,327.00

Other products for "SHANK3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SHANK3
Locus ID 85358
Components

GA113856G1, SHANK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113856G2, SHANK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113856G3, SHANK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001080420, NM_033517
Synonyms DEL22q13.3; KIAA1650; PROSAP2; PSAP2; SPANK-2
Summary This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. provided by RefSeq, Mar 2012
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN235332 SHANK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN235332BN SHANK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN235332LP SHANK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN235332RB SHANK3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN435332 SHANK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products