Human ATAD1 activation kit by CRISPRa

SKU GA113748

ATAD1 CRISPRa kit - CRISPR gene activation of human ATPase family AAA domain containing 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ATAD1
• Locus ID: 84896
• Components:

  GA113748G1, ATAD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113748G2, ATAD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113748G3, ATAD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001321967, NM_001321968, NM_001321969, NM_032810, NR_135914
• UniProt ID: Q8NBU5
• Synonyms: AFDC1; FNP001; THORASE
• Summary: ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).[UniProtKB/Swiss-Prot Function]