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Human CBR4 activation kit by CRISPRa

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SKU
GA113726
CBR4 CRISPRa kit - CRISPR gene activation of human carbonyl reductase 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA810992 CBR4 mouse monoclonal antibody,clone OTI3C10 100 ul
$447.00
RC207442 CBR4 (Myc-DDK-tagged)-Human carbonyl reductase 4 (CBR4)
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Other products for "CBR4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CBR4
Locus ID 84869
Components

GA113726G1, CBR4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113726G2, CBR4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113726G3, CBR4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_032783
UniProt ID Q8N4T8
Synonyms SDR45C1
Summary The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis (PubMed:19571038, PubMed:25203508). Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD (PubMed:25203508). The homotetramer has NADPH-dependent quinone reductase activity (PubMed:19000905). Both homotetramer and the heterotetramer have broad substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) (PubMed:19000905, PubMed:19571038, PubMed:25203508).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN407442 CBR4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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