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Human KBTBD8 activation kit by CRISPRa

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SKU
GA113589
KBTBD8 CRISPRa kit - CRISPR gene activation of human kelch repeat and BTB domain containing 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA370984 KBTBD8 rabbit polyclonal antibody
100 ul
$310.00
RC229306 KBTBD8 (Myc-DDK-tagged)-Human kelch repeat and BTB (POZ) domain containing 8 (KBTBD8)
10 ug
$289.00 $559.00

Other products for "KBTBD8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KBTBD8
Locus ID 84541
Components

GA113589G1, KBTBD8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113589G2, KBTBD8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113589G3, KBTBD8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_032505
UniProt ID Q8NFY9
Synonyms TA-KRP
Summary Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (PubMed:26399832). The BCR(KBTBD8) complex acts by mediating monoubiquitination of NOLC1 and TCOF1: monoubiquitination promotes the formation of a NOLC1-TCOF1 complex that acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN412524 KBTBD8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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