Human CIAO2A activation kit by CRISPRa

SKU
GA113417
CIAO2A CRISPRa kit - CRISPR gene activation of human cytosolic iron-sulfur assembly component 2A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CIAO2A
Locus ID 84191
Components

GA113417G1, CIAO2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113417G2, CIAO2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113417G3, CIAO2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001014812, NM_001289108, NM_032231, NR_110310
UniProt ID Q9H5X1
Synonyms CIA2A
Summary Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227).UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN403357 FAM96A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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