Human KBTBD7 activation kit by CRISPRa

SKU GA113362

KBTBD7 CRISPRa kit - CRISPR gene activation of human kelch repeat and BTB domain containing 7

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: KBTBD7
• Locus ID: 84078
• Components:

  GA113362G1, KBTBD7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA113362G2, KBTBD7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA113362G3, KBTBD7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_032138
• UniProt ID: Q8WVZ9
• Synonyms: DKFZp434E2318
• Summary: The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. [provided by RefSeq, Jul 2016]