Human WDR54 activation kit by CRISPRa

SKU
GA113342
WDR54 CRISPRa kit - CRISPR gene activation of human WD repeat domain 54
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol WDR54
Locus ID 84058
Components

GA113342G1, WDR54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113342G2, WDR54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113342G3, WDR54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001320823, NM_001320824, NM_001320825, NM_032118
UniProt ID Q9H977
Summary When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN408682 WDR54 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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