Human DOCK8 activation kit by CRISPRa

SKU
GA113114
DOCK8 CRISPRa kit - CRISPR gene activation of human dedicator of cytokinesis 8
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DOCK8
Locus ID 81704
Components

GA113114G1, DOCK8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113114G2, DOCK8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113114G3, DOCK8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001190458, NM_001193536, NM_203447
UniProt ID Q8NF50
Synonyms HEL-205; MRD2; ZIR8
Summary This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.provided by RefSeq, Jun 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN422789 DOCK8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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