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Human ITM2C activation kit by CRISPRa

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SKU
GA113094
ITM2C CRISPRa kit - CRISPR gene activation of human integral membrane protein 2C
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA370782 ITM2C rabbit polyclonal antibody
100 ul
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RC200947 ITM2C (Myc-DDK-tagged)-Human integral membrane protein 2C (ITM2C), transcript variant 1
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Other products for "ITM2C"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITM2C
Locus ID 81618
Components

GA113094G1, ITM2C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113094G2, ITM2C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113094G3, ITM2C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001012514, NM_001012516, NM_001287240, NM_001287241, NM_030926
UniProt ID Q9NQX7
Synonyms BRI3; BRICD2C; E25; E25C; ITM3
Summary Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400947 ITM2C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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