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Human CFHR5 activation kit by CRISPRa

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SKU
GA113046
CFHR5 CRISPRa kit - CRISPR gene activation of human complement factor H related 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
$585.00
RC223868 CFHR5 (Myc-DDK-tagged)-Human complement factor H-related 5 (CFHR5)
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Other products for "CFHR5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CFHR5
Locus ID 81494
Components

GA113046G1, CFHR5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113046G2, CFHR5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113046G3, CFHR5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_030787
UniProt ID Q9BXR6
Synonyms CFHL5; CFHR5D; FHR-5; FHR5
Summary This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). provided by RefSeq, Jan 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN423868 CFHR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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